Hospital Outbreak of Middle East Respiratory Syndrome Coronavirus
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Auteurs : Abdullah Assiri [Arabie saoudite] ; Allison Mcgeer [Canada] ; Trish M. Perl [États-Unis] ; Connie S. Price [États-Unis] ; Abdullah A. Al Rabeeah [Arabie saoudite] ; Derek A. T. Cummings [États-Unis] ; Zaki N. Alabdullatif [Arabie saoudite] ; Maher Assad [Arabie saoudite] ; Abdulmohsen Almulhim [Arabie saoudite] ; Hatem Makhdoom [Arabie saoudite] ; Hossam Madani [Arabie saoudite] ; Rafat Alhakeem [Arabie saoudite] ; Jaffar A. Al-Tawfiq [Arabie saoudite] ; Matthew Cotten [Royaume-Uni] ; Simon J. Watson [Royaume-Uni] ; Paul Kellam [Royaume-Uni] ; Alimuddin I. Zumla [Arabie saoudite, Royaume-Uni] ; Ziad A. Memish [Arabie saoudite]Source :
- The New England journal of medicine [ 0028-4793 ] ; 2013.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Médecine.
English descriptors
- KwdEn :
Abstract
BACKGROUND In September 2012, the World Health Organization reported the first cases of pneumonia caused by the novel Middle East respiratory syndrome coronavirus (MERS-CoV). We describe a cluster of health care-acquired MERS-CoV infections. METHODS Medical records were reviewed for clinical and demographic information and determination of potential contacts and exposures. Case patients and contacts were interviewed. The incubation period and serial interval (the time between the successive onset of symptoms in a chain of transmission) were estimated. Viral RNA was sequenced. RESULTS Between April 1 and May 23, 2013, a total of 23 cases of MERS-CoV infection were reported in the eastern province of Saudi Arabia. Symptoms included fever in 20 patients (87%), cough in 20 (87%), shortness of breath in 11 (48%), and gastrointestinal symptoms in 8 (35%); 20 patients (87%) presented with abnormal chest radiographs. As of June 12, a total of 15 patients (65%) had died, 6 (26%) had recovered, and 2 (9%) remained hospitalized. The median incubation period was 5.2 days (95% confidence interval [CI], 1.9 to 14.7), and the serial interval was 7.6 days (95% CI, 2.5 to 23.1). A total of 21 of the 23 cases were acquired by person-to-person transmission in hemodialysis units, intensive care units, or in-patient units in three different health care facilities. Sequencing data from four isolates revealed a single monophyletic clade. Among 217 household contacts and more than 200 health care worker contacts whom we identified, MERS-CoV infection developed in 5 family members (3 with laboratory-confirmed cases) and in 2 health care workers (both with laboratory-confirmed cases). CONCLUSIONS Person-to-person transmission of MERS-CoV can occur in health care settings and may be associated with considerable morbidity. Surveillance and infection-control measures are critical to a global public health response.
Affiliations:
- Arabie saoudite, Canada, Royaume-Uni, États-Unis
- Angleterre, Grand Londres, Maryland, Ontario
- Baltimore, Londres, Toronto
- University College de Londres, Université de Toronto
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Perl</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Departments of Medicine and Pathology, Johns Hopkins University</s1><s2>Baltimore</s2><s3>USA</s3><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Department of Epidemiology, Johns Hopkins University</s1><s2>Baltimore</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Price, Connie S" sort="Price, Connie S" uniqKey="Price C" first="Connie S." last="Price">Connie S. 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Zumla</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Global Center for Mass Gatherings Medicine, Ministry of Health</s1><s3>SAU</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>Arabie saoudite</country><wicri:noRegion>Global Center for Mass Gatherings Medicine, Ministry of Health</wicri:noRegion></affiliation><affiliation wicri:level="4"><inist:fA14 i1="09"><s1>University College London</s1><s3>GBR</s3><sZ>16 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="10"><s1>National Institute for Health Research University College London Hospitals Biomedical Research Centre</s1><s2>London</s2><s3>GBR</s3><sZ>17 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Memish, Ziad A" sort="Memish, Ziad A" uniqKey="Memish Z" first="Ziad A." last="Memish">Ziad A. 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Perl</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Departments of Medicine and Pathology, Johns Hopkins University</s1><s2>Baltimore</s2><s3>USA</s3><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Department of Epidemiology, Johns Hopkins University</s1><s2>Baltimore</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Price, Connie S" sort="Price, Connie S" uniqKey="Price C" first="Connie S." last="Price">Connie S. Price</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Denver Health and University of Colorado Denver</s1><s2>Denver</s2><s3>USA</s3><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Denver Health and University of Colorado Denver</wicri:noRegion></affiliation></author><author><name sortKey="Al Rabeeah, Abdullah A" sort="Al Rabeeah, Abdullah A" uniqKey="Al Rabeeah A" first="Abdullah A." last="Al Rabeeah">Abdullah A. Al Rabeeah</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Global Center for Mass Gatherings Medicine, Ministry of Health</s1><s3>SAU</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>Arabie saoudite</country><wicri:noRegion>Global Center for Mass Gatherings Medicine, Ministry of Health</wicri:noRegion></affiliation></author><author><name sortKey="Cummings, Derek A T" sort="Cummings, Derek A T" uniqKey="Cummings D" first="Derek A. T." last="Cummings">Derek A. T. Cummings</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Department of Epidemiology, Johns Hopkins University</s1><s2>Baltimore</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Alabdullatif, Zaki N" sort="Alabdullatif, Zaki N" uniqKey="Alabdullatif Z" first="Zaki N." last="Alabdullatif">Zaki N. Alabdullatif</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Global Center for Mass Gatherings Medicine, Ministry of Health</s1><s3>SAU</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>Arabie saoudite</country><wicri:noRegion>Global Center for Mass Gatherings Medicine, Ministry of Health</wicri:noRegion></affiliation></author><author><name sortKey="Assad, Maher" sort="Assad, Maher" uniqKey="Assad M" first="Maher" last="Assad">Maher Assad</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Global Center for Mass Gatherings Medicine, Ministry of Health</s1><s3>SAU</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>Arabie saoudite</country><wicri:noRegion>Global Center for Mass Gatherings Medicine, Ministry of Health</wicri:noRegion></affiliation></author><author><name sortKey="Almulhim, Abdulmohsen" sort="Almulhim, Abdulmohsen" uniqKey="Almulhim A" first="Abdulmohsen" last="Almulhim">Abdulmohsen Almulhim</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Global Center for Mass Gatherings Medicine, Ministry of Health</s1><s3>SAU</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>Arabie saoudite</country><wicri:noRegion>Global Center for Mass Gatherings Medicine, Ministry of Health</wicri:noRegion></affiliation></author><author><name sortKey="Makhdoom, Hatem" sort="Makhdoom, Hatem" uniqKey="Makhdoom H" first="Hatem" last="Makhdoom">Hatem Makhdoom</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Global Center for Mass Gatherings Medicine, Ministry of Health</s1><s3>SAU</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>Arabie saoudite</country><wicri:noRegion>Global Center for Mass Gatherings Medicine, Ministry of Health</wicri:noRegion></affiliation></author><author><name sortKey="Madani, Hossam" sort="Madani, Hossam" uniqKey="Madani H" first="Hossam" last="Madani">Hossam Madani</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Global Center for Mass Gatherings Medicine, Ministry of Health</s1><s3>SAU</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>Arabie saoudite</country><wicri:noRegion>Global Center for Mass Gatherings Medicine, Ministry of Health</wicri:noRegion></affiliation></author><author><name sortKey="Alhakeem, Rafat" sort="Alhakeem, Rafat" uniqKey="Alhakeem R" first="Rafat" last="Alhakeem">Rafat Alhakeem</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Global Center for Mass Gatherings Medicine, Ministry of Health</s1><s3>SAU</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>Arabie saoudite</country><wicri:noRegion>Global Center for Mass Gatherings Medicine, Ministry of Health</wicri:noRegion></affiliation></author><author><name sortKey="Al Tawfiq, Jaffar A" sort="Al Tawfiq, Jaffar A" uniqKey="Al Tawfiq J" first="Jaffar A." last="Al-Tawfiq">Jaffar A. Al-Tawfiq</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Saudi Aramco Medical Service Organization</s1><s2>Dahran</s2><s3>SAU</s3><sZ>13 aut.</sZ></inist:fA14><country>Arabie saoudite</country><wicri:noRegion>Saudi Aramco Medical Service Organization</wicri:noRegion></affiliation></author><author><name sortKey="Cotten, Matthew" sort="Cotten, Matthew" uniqKey="Cotten M" first="Matthew" last="Cotten">Matthew Cotten</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Wellcome Trust Sanger Institute</s1><s2>Hinxton</s2><s3>GBR</s3><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Wellcome Trust Sanger Institute</wicri:noRegion></affiliation></author><author><name sortKey="Watson, Simon J" sort="Watson, Simon J" uniqKey="Watson S" first="Simon J." last="Watson">Simon J. Watson</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Wellcome Trust Sanger Institute</s1><s2>Hinxton</s2><s3>GBR</s3><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Wellcome Trust Sanger Institute</wicri:noRegion></affiliation></author><author><name sortKey="Kellam, Paul" sort="Kellam, Paul" uniqKey="Kellam P" first="Paul" last="Kellam">Paul Kellam</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Wellcome Trust Sanger Institute</s1><s2>Hinxton</s2><s3>GBR</s3><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Wellcome Trust Sanger Institute</wicri:noRegion></affiliation><affiliation wicri:level="4"><inist:fA14 i1="09"><s1>University College London</s1><s3>GBR</s3><sZ>16 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Zumla, Alimuddin I" sort="Zumla, Alimuddin I" uniqKey="Zumla A" first="Alimuddin I." last="Zumla">Alimuddin I. Zumla</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Global Center for Mass Gatherings Medicine, Ministry of Health</s1><s3>SAU</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>Arabie saoudite</country><wicri:noRegion>Global Center for Mass Gatherings Medicine, Ministry of Health</wicri:noRegion></affiliation><affiliation wicri:level="4"><inist:fA14 i1="09"><s1>University College London</s1><s3>GBR</s3><sZ>16 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="10"><s1>National Institute for Health Research University College London Hospitals Biomedical Research Centre</s1><s2>London</s2><s3>GBR</s3><sZ>17 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Memish, Ziad A" sort="Memish, Ziad A" uniqKey="Memish Z" first="Ziad A." last="Memish">Ziad A. Memish</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Global Center for Mass Gatherings Medicine, Ministry of Health</s1><s3>SAU</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ><sZ>12 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>Arabie saoudite</country><wicri:noRegion>Global Center for Mass Gatherings Medicine, Ministry of Health</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Al-Faisal University</s1><s2>Riyadh</s2><s3>SAU</s3><sZ>18 aut.</sZ></inist:fA14><country>Arabie saoudite</country><wicri:noRegion>Al-Faisal University</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">The New England journal of medicine</title><title level="j" type="abbreviated">N. Engl. j. med.</title><idno type="ISSN">0028-4793</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">The New England journal of medicine</title><title level="j" type="abbreviated">N. Engl. j. med.</title><idno type="ISSN">0028-4793</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Coronavirus</term><term>Medicine</term><term>Middle east</term><term>Nosocomial infection</term><term>Respiratory system</term><term>Respiratory tract</term><term>Syndrome</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Infection nosocomiale</term><term>Moyen Orient</term><term>Appareil respiratoire</term><term>Voie respiratoire</term><term>Syndrome</term><term>Coronavirus</term><term>Médecine</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Médecine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">BACKGROUND In September 2012, the World Health Organization reported the first cases of pneumonia caused by the novel Middle East respiratory syndrome coronavirus (MERS-CoV). We describe a cluster of health care-acquired MERS-CoV infections. METHODS Medical records were reviewed for clinical and demographic information and determination of potential contacts and exposures. Case patients and contacts were interviewed. The incubation period and serial interval (the time between the successive onset of symptoms in a chain of transmission) were estimated. Viral RNA was sequenced. RESULTS Between April 1 and May 23, 2013, a total of 23 cases of MERS-CoV infection were reported in the eastern province of Saudi Arabia. Symptoms included fever in 20 patients (87%), cough in 20 (87%), shortness of breath in 11 (48%), and gastrointestinal symptoms in 8 (35%); 20 patients (87%) presented with abnormal chest radiographs. As of June 12, a total of 15 patients (65%) had died, 6 (26%) had recovered, and 2 (9%) remained hospitalized. The median incubation period was 5.2 days (95% confidence interval [CI], 1.9 to 14.7), and the serial interval was 7.6 days (95% CI, 2.5 to 23.1). A total of 21 of the 23 cases were acquired by person-to-person transmission in hemodialysis units, intensive care units, or in-patient units in three different health care facilities. Sequencing data from four isolates revealed a single monophyletic clade. Among 217 household contacts and more than 200 health care worker contacts whom we identified, MERS-CoV infection developed in 5 family members (3 with laboratory-confirmed cases) and in 2 health care workers (both with laboratory-confirmed cases). CONCLUSIONS Person-to-person transmission of MERS-CoV can occur in health care settings and may be associated with considerable morbidity. Surveillance and infection-control measures are critical to a global public health response.</div></front></TEI><affiliations><list><country><li>Arabie saoudite</li><li>Canada</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Grand Londres</li><li>Maryland</li><li>Ontario</li></region><settlement><li>Baltimore</li><li>Londres</li><li>Toronto</li></settlement><orgName><li>University College de Londres</li><li>Université de Toronto</li></orgName></list><tree><country name="Arabie saoudite"><noRegion><name sortKey="Assiri, Abdullah" sort="Assiri, Abdullah" uniqKey="Assiri A" first="Abdullah" last="Assiri">Abdullah Assiri</name></noRegion><name sortKey="Al Rabeeah, Abdullah A" sort="Al Rabeeah, Abdullah A" uniqKey="Al Rabeeah A" first="Abdullah A." last="Al Rabeeah">Abdullah A. Al Rabeeah</name><name sortKey="Al Tawfiq, Jaffar A" sort="Al Tawfiq, Jaffar A" uniqKey="Al Tawfiq J" first="Jaffar A." last="Al-Tawfiq">Jaffar A. Al-Tawfiq</name><name sortKey="Alabdullatif, Zaki N" sort="Alabdullatif, Zaki N" uniqKey="Alabdullatif Z" first="Zaki N." last="Alabdullatif">Zaki N. Alabdullatif</name><name sortKey="Alhakeem, Rafat" sort="Alhakeem, Rafat" uniqKey="Alhakeem R" first="Rafat" last="Alhakeem">Rafat Alhakeem</name><name sortKey="Almulhim, Abdulmohsen" sort="Almulhim, Abdulmohsen" uniqKey="Almulhim A" first="Abdulmohsen" last="Almulhim">Abdulmohsen Almulhim</name><name sortKey="Assad, Maher" sort="Assad, Maher" uniqKey="Assad M" first="Maher" last="Assad">Maher Assad</name><name sortKey="Madani, Hossam" sort="Madani, Hossam" uniqKey="Madani H" first="Hossam" last="Madani">Hossam Madani</name><name sortKey="Makhdoom, Hatem" sort="Makhdoom, Hatem" uniqKey="Makhdoom H" first="Hatem" last="Makhdoom">Hatem Makhdoom</name><name sortKey="Memish, Ziad A" sort="Memish, Ziad A" uniqKey="Memish Z" first="Ziad A." last="Memish">Ziad A. Memish</name><name sortKey="Memish, Ziad A" sort="Memish, Ziad A" uniqKey="Memish Z" first="Ziad A." last="Memish">Ziad A. Memish</name><name sortKey="Zumla, Alimuddin I" sort="Zumla, Alimuddin I" uniqKey="Zumla A" first="Alimuddin I." last="Zumla">Alimuddin I. Zumla</name></country><country name="Canada"><region name="Ontario"><name sortKey="Mcgeer, Allison" sort="Mcgeer, Allison" uniqKey="Mcgeer A" first="Allison" last="Mcgeer">Allison Mcgeer</name></region></country><country name="États-Unis"><region name="Maryland"><name sortKey="Perl, Trish M" sort="Perl, Trish M" uniqKey="Perl T" first="Trish M." last="Perl">Trish M. Perl</name></region><name sortKey="Cummings, Derek A T" sort="Cummings, Derek A T" uniqKey="Cummings D" first="Derek A. T." last="Cummings">Derek A. T. Cummings</name><name sortKey="Perl, Trish M" sort="Perl, Trish M" uniqKey="Perl T" first="Trish M." last="Perl">Trish M. Perl</name><name sortKey="Price, Connie S" sort="Price, Connie S" uniqKey="Price C" first="Connie S." last="Price">Connie S. Price</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Cotten, Matthew" sort="Cotten, Matthew" uniqKey="Cotten M" first="Matthew" last="Cotten">Matthew Cotten</name></noRegion><name sortKey="Kellam, Paul" sort="Kellam, Paul" uniqKey="Kellam P" first="Paul" last="Kellam">Paul Kellam</name><name sortKey="Kellam, Paul" sort="Kellam, Paul" uniqKey="Kellam P" first="Paul" last="Kellam">Paul Kellam</name><name sortKey="Watson, Simon J" sort="Watson, Simon J" uniqKey="Watson S" first="Simon J." last="Watson">Simon J. Watson</name><name sortKey="Zumla, Alimuddin I" sort="Zumla, Alimuddin I" uniqKey="Zumla A" first="Alimuddin I." last="Zumla">Alimuddin I. Zumla</name><name sortKey="Zumla, Alimuddin I" sort="Zumla, Alimuddin I" uniqKey="Zumla A" first="Alimuddin I." last="Zumla">Alimuddin I. Zumla</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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